CTCF is a ubiquitously expressed chromatin-binding factor that contains 11 zinc fingers (ZFs) and is conserved from Drosophila to human 1,2. CTCF regulates transcription through promoter binding 3,4 ...

Substantive improvements in the treatment of pediatric diseases such as leukemia and sarcomas have led to greater numbers of survivors, many of whom have reduced fertility. One means of preserving the ...

Torsion of the testis is a condition where the testis spins resulting in twisting of the spermatic cord. It is essential to know in brief about the development and the structure of the testis and ...

A team of researchers from the University of Aveiro and the University of Porto, both in Portugal, and the University of Birmingham in the U.K. has found that for humans, the brain and testis have the ...

Polyorchidism is a rare condition that causes males to be born with more than two testicles. Usually, the condition involves three testicles. People with polyorchidism are born with more than two ...

Despite 15 years of international research on the topic, there are no guidelines on the management of boys with NPT. The management of boys with this disorder is still controversial, and in this ...

When a scrotum is empty this indicates an undescended testis. This occurs when a testis never moved down in to the scrotum as the male developed, or moves back up out of the scrotum and into the ...

Undescended testis, which is a risk factor for testicular cancer, is usually treated surgically, but whether the age at treatment has any effect on the risk is unclear. We studied the relation between ...

A breakthrough study published in PLoS Biology demonstrates that rat testis tissue frozen for over 20 years can be successfully transplanted into infertile mice to regenerate and produce sperms.