Researchers identified OLE, a molecule derived from the PM20D1 gene, that reprograms microglia into a more protective state ...

According to the study published by Sciencedaily, OLE helps microglia surround and contain beta-amyloid plaques, reducing ...

Alzheimer's disease (AD) is a devastating neurodegenerative disorder heavily characterized by amyloid-beta (Aβ) plaques, ...

Scientists have uncovered a surprising clue that may help explain why multiple sclerosis (MS) progresses rapidly in some people but not others. In brain tissue from patients with severe MS, ...

A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s ...

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). Current therapies for relapsing MS primarily target the peripheral immune system but have consistently ...

GV1001 is a peptide consisting of 16 amino acids derived from the catalytic subunit of human telomerase reverse transcriptase. A recent phase II clinical trial in patients with Alzheimer disease (AD) ...

Scientists in Spain and Switzerland have identified a new experimental molecule that could help restore the brain’s natural defence system against Alzheimer’s disease, offering a potential new ...

The findings shed light on a topic of growing concern for Americans while also exposing a previously "unclear" relationship.

A chance discovery at Nagoya University in Japan has shown that a well-known brain enzyme has a hidden ability: It builds a ...

Microglia, the resident immune sentinels of the central nervous system (CNS), have emerged as central regulators of immune–neural interactions and ...

Two FDA-approved cancer drugs, letrozole and irinotecan, reduced tau tangles and improved memory in mice engineered to carry ...