Background Fibrosis and tumour innervation are two features of the tumour microenvironment (TME) that contribute directly to ...
I read the GOULASH trial with great interest. This multicentre, double-blind randomised clinical trial compared early high-energy enteral nutrition (30 kcal/kg/day) with a gradually increasing energy ...
Background: Patients with irritable bowel syndrome (IBS) often feel they have some form of dietary intolerance and frequently try exclusion diets. Tests attempting to predict food sensitivity in IBS ...
7 Department of Paediatrics, St George's Hospital, London, UK 8 Department of Gastroenterology, St. Mary's Hospital, London, UK 9 Department Gastroenterology, University Hospital of North Tees, UK The ...
Objective In the tumour microenvironment, critical drivers of immune escape include the oncogenic activity of the tumour cell-intrinsic osteopontin (OPN), the expression of programmed death ligand 1 ...
a Inflammatory Bowel Disease Study Group, Royal Free Hospital School of Medicine, London, UK, b Gastroenterology Unit, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK Dr R N Allan, Queen Elizabeth ...
The effect of tea on iron absorption was studied in human volunteers. Absorption from solutions of FeCl3 and FeSO4, bread, a meal of rice with potato and onion soup, and uncooked haemoglobin was ...
Afferent fibres convey sensory information from the upper gastrointestinal tract to the central nervous system but the nature of this information is different for vagal and spinal pathways. Vagal ...
Objective Our previous studies have identified CXCL8 as the crucial chemokine responsible for gastric cancer metastasis mediated by loss of RACK1. However, the regulatory effect of CXCL8 on immune ...
The goal of this review is to describe barrier function of the intestine, the structure of the tight junction, methods to evaluate intestinal permeability, and most importantly the relevance of ...
The aim of this study was to establish the relative importance of risk factors for mortality after acute upper gastrointestinal haemorrhage, and to formulate a simple numerical scoring system that ...
Correspondence to Dr Jonathan D Schertzer, McMaster University Faculty of Health Sciences, Hamilton, ON L8S 4K1, Canada; schertze{at}mcmaster.ca Microbiota are a source of low-grade inflammation ...
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