Synaptic plasticity, the ability of synapses to strengthen or weaken over time in response to changes in their activity, is a central foundation of learning and memory. At synapses, presynaptic cells ...

For all its mysteries, the brain can sometimes be described through simple metaphors. For example, communication between neurons works in many ways like a busy shipping depot: components come in, ...

Bioengineers and neuroscientists at the Wu Tsai Neurosciences Institute at Stanford University have developed a highly sensitive tool for detecting brain cells' subtlest electrical signals. Published ...

Increased levels of bioactive lipids produced naturally in the body, which affect excitatory transmission between brain cells, promote mental disorders. However, this mechanism can be rebalanced by ...

Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies (CAPS) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with ...

While the role of barrier function in establishing a protective, nutrient-rich, and ionically balanced environment for neurons has been appreciated for some time, little is known about how signaling ...

A new study reveals that targeting the SLC6A20 glycine transporter with ASOs restores NMDAR function and reverses adult autism behaviors.

A) Taste tissue of wild-type mice and taste cell synaptic dysfunction mice (SNAP-cKO). In SNAP-cKO mice, the number of sour-sensing cells is reduced. B) Gustatory nerve responses to various taste ...