Medical Xpress

Dietary zinc protects against Streptococcus pneumoniae infection

Researchers have uncovered a crucial link between dietary zinc intake and protection against Streptococcus pneumoniae, the primary bacterial cause of pneumonia. Globally, it is estimated that nearly ...

Merck's pneumococcal vaccine wins US approval for high-risk children, teens

June 18 (Reuters) - Drugmaker Merck said on Thursday the U.S. health regulator has approved an expanded use of its ...
Medscape

Vaccine Protection Extended to High-Risk Children and Teens

The FDA has approved an expanded indication for a 21-valent pneumococcal conjugate vaccine for children and teens aged 2-17 ...

FDA expands Merck pneumococcal shot label to include at-risk children and teens

The U.S. FDA on Thursday approved an expanded indication for Merck & Co Inc.’s MRK Capvaxive, extending its use to children ...
Medical Xpress

Asymptomatic adults may be reservoirs of Streptococcus pneumoniae

Streptococcus pneumoniae is a major human pathogen and a leading cause of several infectious diseases including pneumonia, the third-leading cause of death in Portugal. In Europe, S. pneumoniae is the ...

U.S. FDA Approves an Additional Indication for CAPVAXIVE® (Pneumococcal 21-valent Conjugate Vaccine) in Children and Adolescents Aged 2 through 17 at Increa…

Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced that the U.S. Food and Drug ...
News Medical

Study suggests a novel strategy to combat multidrug-resistant S. pneumoniae infections

Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually. A study publishing March 16 th in the open access journal PLOS Biology by Carlos J.
Kaleido Scope

An atlas of S. pneumoniae and host gene expression during colonization and disease

To understand how this pathogen adapts to different locations in the body, and also how the host responds to the invading microbe, researchers at the University of Alabama at Birmingham, the ...
News Medical

Withdrawal of COVID-19 mitigation measures resulted in a rebound in Streptococcus pneumoniae cases in Germany

In a recent study posted to the medRxiv* preprint server, researchers from Germany conducted a population-based surveillance study to ascertain the etiology of community-acquired pneumonia (CAP) ...
Nature

Polyamine transporter in Streptococcus pneumoniae is essential for evading early innate immune responses in pneumococcal pneumonia

Table 1 Comparison of significantly altered cytokine/chemokine concentrations in lung of C57BL/6 mice infected with TIGR4 WT and ∆potABCD strains 4 h p.i. Full size ...
Nature

Streptococcus pneumoniae Cell Wall-Localized Trigger Factor Elicits a Protective Immune Response and Contributes to Bacterial Adhesion to the Host

Trigger factor (TF) has a known cytoplasmic function as a chaperone. In a previous study we showed that pneumococcal TF is also cell-wall localized and this finding combined with the immunogenic ...
Science Daily

Dietary zinc protects against Streptococcus pneumoniae infection, study finds

Researchers have uncovered a crucial link between dietary zinc intake and protection against Streptococcus pneumoniae, the primary bacterial cause of pneumonia. Researchers have uncovered a crucial ...