We have gone further than ever before in creating life that is unlike anything that has evolved naturally. The genome of an Escherichia coli bacterium has been redesigned on a computer to use just 57 ...

If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and the middle. Is everything packed? What time should we leave? Will there be ...

The ability to precisely edit the genomes of bacteria has long been a goal of microbiologists. Such technology would enable scientists to make new inroads into studying disease, developing sustainable ...

Escherichia coli relies on a sophisticated suite of pathways to maintain genomic integrity in the face of endogenous metabolic by-products and exogenous agents. Direct reversal mechanisms, exemplified ...

Genetic recombination in Escherichia coli is a fundamental process that repairs DNA damage, maintains genome integrity and generates genetic diversity. Two principal pathways operate in concert: the ...

Scientists have uncovered new clues about why diabetic foot infections can become so severe and difficult to treat. By analyzing the DNA of E. coli bacteria taken from infected wounds around the world ...